The human endometrium as a fertility-determining factor.

I-34: Interactorme of Human Embryo Implan Implantation:Pathways,Networks

Background: A prerequisite for successful embryo implantation is adequate preparation of receptive endometrium and the establishment and maintenance of a viable embryo. The success of implantation further relies upon a two-way dialogue between the embryo and uterus. However, molecular bases of these preimplantation and implantation processes in humans are not well known. Materials and Methods: ...

Ultrastructural Modifications of Human Endometrium during the Window of Implantation

The endometrium is a highly dynamic tissue empowered with the capacity to undergo cyclic dramatic changes in response to ovarian steroid hormones, ultimately aiming to create a window of receptivity for blastocyst implantation. Intensive research has been performed to understand and establish morphological and molecular correlates of embryo implantation. However, it still remains a biological m...

I-30: Human Endometrial Receptivity:from The Basic Research to Clinical Translation

The endometrium is a hormonally regulated organ that is non-adhesive to embryos throughout most of the menstrual cycle in humans. Endometrial receptivity refers to a hormone-limited period in which the endometrial tissue acquires a functional and transient ovarian steroid-dependent status allowing blastocyst adhesion. Functional genomic studies of human endometrium in natural cycles have demons...

Low Doses of Celecoxib Stimulate Human Endometrium Growth in A Three-Dimensional Culture Model

I-24: New Molecular Aspects in Recurrent Pregnancy Loss

Background Recurrent pregnancy loss (RPL) is usually defined as three or more consecutive pregnancy losses before 20th gestational week. Many etiological factors have been considered as cause of RPL including genetic factors, uterine anatomical defects, endocrine abnormalities, thrombotic and immunologic factors. Nevertheless, the cause of RPL remains unknown in around half of the patients desp...